Sestamibi Parathyroid Scan
Sestamibi Parathyroid Scan
Molecular Diagnostics and Therapy
Disorders of the parathyroid glands can lead to significant metabolic imbalance, particularly involving calcium regulation. Early and accurate localization of abnormal parathyroid tissue is essential for effective treatment planning. A Sestamibi Parathyroid Scan is a highly sensitive nuclear medicine imaging procedure used to identify overactive parathyroid glands. At Molecular Diagnostics and Therapy, advanced parathyroid imaging supports precise diagnosis and minimally invasive surgical planning.
Understanding the Parathyroid Glands
The parathyroid glands are four small glands located behind the thyroid gland in the neck. These glands regulate calcium levels in the blood through secretion of parathyroid hormone.
When one or more glands become overactive, a condition known as hyperparathyroidism develops. This may cause:
Elevated blood calcium levels
Kidney stones
Bone weakness
Fatigue
Abdominal discomfort
Accurate localization of the abnormal gland is crucial before surgery.
What Is a Sestamibi Parathyroid Scan?
A Sestamibi Parathyroid Scan is a nuclear medicine test that uses a radiotracer known as Technetium-99m sestamibi. The tracer is injected into a vein and selectively accumulates in overactive parathyroid tissue.
Imaging is performed using a gamma camera at specific time intervals. Abnormal glands retain the tracer longer than normal thyroid tissue, allowing precise localization.
At Molecular Diagnostics and Therapy, advanced imaging protocols ensure high-quality diagnostic results.
Why Is This Scan Performed?
The scan is recommended for:
Primary hyperparathyroidism
Secondary hyperparathyroidism
Preoperative localization before parathyroid surgery
Persistent or recurrent hyperparathyroidism after surgery
Precise identification of the abnormal gland supports targeted surgical removal and reduces the need for extensive neck exploration.
How the Procedure Works
Intravenous injection of Technetium-99m sestamibi
Early imaging phase to assess tracer distribution
Delayed imaging phase to evaluate tracer retention
Image interpretation by nuclear medicine specialists
In some cases, SPECT or SPECT-CT imaging may be performed to improve three-dimensional localization.
Strict safety and quality standards followed at Molecular Diagnostics and Therapy ensure reliable imaging outcomes.
Advantages of Sestamibi Parathyroid Scan
High sensitivity for detecting parathyroid adenomas
Accurate preoperative localization
Minimally invasive surgical guidance
Reduced operative time
Lower risk of surgical complications
This functional imaging method provides valuable information beyond ultrasound alone.
Safety Profile
The radiotracer dose used in this scan is low and remains within established safety guidelines. The procedure is generally well tolerated. Most patients resume normal activities shortly after completion.
At Molecular Diagnostics and Therapy, patient safety, comfort, and diagnostic excellence remain central priorities.
Clinical Importance
Successful treatment of hyperparathyroidism often depends on precise identification of the abnormal gland. A Sestamibi Parathyroid Scan enhances surgical accuracy and improves patient outcomes.
Comprehensive nuclear medicine services at Molecular Diagnostics and Therapy support collaboration between endocrinologists, surgeons, and imaging specialists to ensure optimal care.
Conclusion
A Sestamibi Parathyroid Scan is an essential diagnostic tool for evaluating hyperparathyroidism and guiding minimally invasive surgery. By identifying overactive parathyroid tissue with high accuracy, this imaging technique plays a vital role in modern endocrine care.
Through advanced nuclear medicine expertise, Molecular Diagnostics and Therapy continues to provide precision-focused imaging solutions that enhance diagnosis and improve patient outcomes.